PHARMACOVIGILANCE SIGNALS OF THE OPIOID EPIDEMIC OVER 10 YEARS: DATA MINING METHODS IN THE ANALYSIS OF PHARMACOVIGILANCE DATASETS COLLECTING ADVERSE DRUG REACTIONS (ADRS) REPORTED TO EUDRAVIGILANCE (EV) AND THE FDA ADVERSE EVENT REPORTING SYSTEM (FAERS)

In the past twenty years, the consumption of opioid medications has reached significant proportions, leading to a rise in drug misuse and abuse and increased opioid dependence and related fatalities.Thus, the purpose of this study was to determine whether there are pharmacovigilance signals of abuse, misuse, and dependence and their nature for the

The aim of this study was to assess the utility of cementum layers for estimating age at death of remains from an archaeological site.Variability in cementum layer Grape Seed Extract counts due to interobserver error and variation among dental regions were analyzed.Interobserver error was later incorporated into age ranges based on counts of cement

Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment in the developed world.The two forms of advanced AMD, geographic atrophy and neovascular AMD, represent different pathological processes in the macula that lead to loss of central vision.Soft drusen, characterized by deposits in the macula without visu

Cities are strange places, maximizing density and attachment to place on the one hand and using these very conditions as a basis for wide-ranging movements and connectivity in the settlement tiers of their urban landscape as much as in external flows for often increasing distances on the other.Hospitable to such urban conditions, and profiting from